Engineering exosomes for targeted drug delivery

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Surface Engineering of Liposomal Formulations for Targeted Drug Delivery

Liposomes, basically including lecithin and cholesterol, are classic nanovesicles to treat some diseases clinically. As the first FDA approved nanomedicine, Doxil® (Doxorubicin HCl Liposome Injection) is a successful formulation to inhibit the development of some cancer and improve the life time of the patients after tumor surgery [1]. However, the non-specific accumulation of liposomes in Reti...

Aptamers for Targeted Drug Delivery

Aptamers are a class of therapeutic oligonucleotides that form specific three-dimensional structures that are dictated by their sequences. They are typically generated by an iterative screening process of complex nucleic acid libraries employing a process termed Systemic Evolution of Ligands by Exponential Enrichment (SELEX). SELEX has traditionally been performed using purified proteins, and c...

advances in targeted drug delivery

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